NIA Mouse Gene Index, mm9

1460. U004298
Annotation: transforming growth factor, beta receptor I     Gene?: Yes     Source: NM_009370    Symbol:  Tgfbr1
Chromosome: chr4   Strand: +    Start: 47366093    End: 47427803
List: Positive strand of chr4 (N=6286)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR002290 - Serine/threonine protein kinase
IPR000472 - TGF-beta receptor/activin receptor, type I/II
IPR003605 - TGF beta receptor, GS motif
IPR000719 - Protein kinase, core
IPR001245 - Tyrosine protein kinase

GO-Ontologies
GO:0048870 - cell motility
GO:0043235 - receptor complex
GO:0004672 - protein kinase activity
GO:0007507 - heart development
GO:0070723 - response to cholesterol
GO:0005923 - tight junction
GO:0007179 - transforming growth factor beta receptor signaling pathway
GO:0001824 - blastocyst development
GO:0030199 - collagen fibril organization
GO:0005515 - protein binding
GO:0030307 - positive regulation of cell growth
GO:0000166 - nucleotide binding
GO:0051272 - positive regulation of cellular component movement
GO:0016301 - kinase activity
GO:0018105 - peptidyl-serine phosphorylation
GO:0048701 - embryonic cranial skeleton morphogenesis
GO:0006915 - apoptotic process
GO:0045602 - negative regulation of endothelial cell differentiation
GO:0045893 - positive regulation of transcription, DNA-dependent
GO:0016020 - membrane
GO:0005025 - transforming growth factor beta receptor activity, type I
GO:0016323 - basolateral plasma membrane
GO:0048705 - skeletal system morphogenesis
GO:0008354 - germ cell migration
GO:0018107 - peptidyl-threonine phosphorylation
GO:0060017 - parathyroid gland development
GO:0006355 - regulation of transcription, DNA-dependent
GO:0016324 - apical plasma membrane
GO:0045885 - positive regulation of survival gene product expression
GO:0006468 - protein phosphorylation
GO:0070411 - I-SMAD binding
GO:0031396 - regulation of protein ubiquitination
GO:0051491 - positive regulation of filopodium assembly
GO:0009791 - post-embryonic development
GO:0016310 - phosphorylation
GO:0046332 - SMAD binding
GO:0008284 - positive regulation of cell proliferation
GO:0060389 - pathway-restricted SMAD protein phosphorylation
GO:0043627 - response to estrogen stimulus
GO:0005886 - plasma membrane
GO:0044459 - plasma membrane part
GO:0006917 - induction of apoptosis
GO:0004872 - receptor activity
GO:0043234 - protein complex
GO:0004675 - transmembrane receptor protein serine/threonine kinase activity
GO:0007165 - signal transduction
GO:0031625 - ubiquitin protein ligase binding
GO:0048844 - artery morphogenesis
GO:0060021 - palate development
GO:0048663 - neuron fate commitment
GO:0043393 - regulation of protein binding
GO:0010862 - positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0005524 - ATP binding
GO:0005024 - transforming growth factor beta-activated receptor activity
GO:0048538 - thymus development
GO:0016021 - integral to membrane
GO:0060037 - pharyngeal system development
GO:0016772 - transferase activity, transferring phosphorus-containing groups
GO:0016740 - transferase activity
GO:0032403 - protein complex binding
GO:0046777 - protein autophosphorylation
GO:0030054 - cell junction
GO:0050431 - transforming growth factor beta binding
GO:0009790 - embryo development
GO:0004674 - protein serine/threonine kinase activity
GO:0001837 - epithelial to mesenchymal transition
GO:0000186 - activation of MAPKK activity
GO:0051897 - positive regulation of protein kinase B signaling cascade
GO:0009952 - anterior/posterior pattern specification
GO:0043066 - negative regulation of apoptotic process
GO:0040008 - regulation of growth
GO:0046872 - metal ion binding
GO:0030154 - cell differentiation
GO:0005114 - type II transforming growth factor beta receptor binding
GO:0001822 - kidney development
GO:0001701 - in utero embryonic development
GO:0001501 - skeletal system development
GO:0042981 - regulation of apoptotic process
GO:0046982 - protein heterodimerization activity
GO:0010468 - regulation of gene expression
GO:0060391 - positive regulation of SMAD protein import into nucleus