NIA Mouse Gene Index, mm9

2714. U004508
Annotation: endothelial-specific receptor tyrosine kinase     Gene?: Yes     Source: NM_013690    Symbol:  Tek
Chromosome: chr4   Strand: +    Start: 94405974    End: 94541667
List: Positive strand of chr4 (N=6286)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR002290 - Serine/threonine protein kinase
IPR003961 - Fibronectin, type III
IPR013098 - Immunoglobulin I-set
IPR011019 - KIND
IPR003599 - Immunoglobulin subtype
IPR000719 - Protein kinase, core
IPR001245 - Tyrosine protein kinase

GO-Ontologies
GO:0030097 - hemopoiesis
GO:0070374 - positive regulation of ERK1 and ERK2 cascade
GO:0045765 - regulation of angiogenesis
GO:0007507 - heart development
GO:0004672 - protein kinase activity
GO:0007160 - cell-matrix adhesion
GO:0005524 - ATP binding
GO:0005515 - protein binding
GO:0000166 - nucleotide binding
GO:0016301 - kinase activity
GO:0051259 - protein oligomerization
GO:0001570 - vasculogenesis
GO:0016021 - integral to membrane
GO:0010595 - positive regulation of endothelial cell migration
GO:0014068 - positive regulation of phosphatidylinositol 3-kinase cascade
GO:0045121 - membrane raft
GO:0016020 - membrane
GO:0005902 - microvillus
GO:0001525 - angiogenesis
GO:0016772 - transferase activity, transferring phosphorus-containing groups
GO:0016323 - basolateral plasma membrane
GO:0016740 - transferase activity
GO:0001569 - patterning of blood vessels
GO:0046777 - protein autophosphorylation
GO:0033138 - positive regulation of peptidyl-serine phosphorylation
GO:0010740 - positive regulation of intracellular protein kinase cascade
GO:0016324 - apical plasma membrane
GO:0032526 - response to retinoic acid
GO:0006468 - protein phosphorylation
GO:0051897 - positive regulation of protein kinase B signaling cascade
GO:0005622 - intracellular
GO:0018108 - peptidyl-tyrosine phosphorylation
GO:0006916 - anti-apoptosis
GO:0009986 - cell surface
GO:0030334 - regulation of cell migration
GO:0005887 - integral to plasma membrane
GO:0048014 - Tie receptor signaling pathway
GO:0016310 - phosphorylation
GO:0001935 - endothelial cell proliferation
GO:0045766 - positive regulation of angiogenesis
GO:0004714 - transmembrane receptor protein tyrosine kinase activity
GO:0016337 - cell-cell adhesion
GO:0019838 - growth factor binding
GO:0004713 - protein tyrosine kinase activity
GO:2000352 - negative regulation of endothelial cell apoptosis
GO:0043627 - response to estrogen stimulus
GO:0045785 - positive regulation of cell adhesion
GO:0035556 - intracellular signal transduction
GO:0007169 - transmembrane receptor protein tyrosine kinase signaling pathway
GO:0001936 - regulation of endothelial cell proliferation
GO:0060347 - heart trabecula formation
GO:0001934 - positive regulation of protein phosphorylation
GO:0004872 - receptor activity
GO:0030949 - positive regulation of vascular endothelial growth factor receptor signaling pathway