NIA Mouse Gene Index, mm9

990. U005409
Annotation: interleukin 6     Gene?: Yes     Source: NM_031168    Symbol:  Il6
Chromosome: chr5   Strand: +    Start: 30339653    End: 30346521
List: Positive strand of chr5 (N=5877)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR009079 - Four-helical cytokine
IPR012351 - Cytokine, four-helical bundle
IPR003574 - Interleukin-6
IPR003573 - Interleukin-6/G-CSF/MGF

GO-Ontologies
GO:0042832 - defense response to protozoan
GO:0005138 - interleukin-6 receptor binding
GO:0005125 - cytokine activity
GO:0008083 - growth factor activity
GO:0005515 - protein binding
GO:0050731 - positive regulation of peptidyl-tyrosine phosphorylation
GO:0006953 - acute-phase response
GO:0005576 - extracellular region
GO:0006955 - immune response
GO:0045893 - positive regulation of transcription, DNA-dependent
GO:0005615 - extracellular space
GO:0001781 - neutrophil apoptosis
GO:0046888 - negative regulation of hormone secretion
GO:0045079 - negative regulation of chemokine biosynthetic process
GO:0033138 - positive regulation of peptidyl-serine phosphorylation
GO:0045944 - positive regulation of transcription from RNA polymerase II promoter
GO:0045630 - positive regulation of T-helper 2 cell differentiation
GO:0043410 - positive regulation of MAPKKK cascade