NIA Mouse Gene Index, mm9

1034. U005409
Annotation: interleukin 6     Gene?: Yes     Source: NM_031168    Symbol:  Il6
Chromosome: chr5   Strand: +    Start: 30339653    End: 30346521
List: Positive strand of chr5 (N=6089)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR003573 - Interleukin-6/G-CSF/MGF

GO-Ontologies
GO:0051091 - positive regulation of sequence-specific DNA binding transcription factor activity
GO:0005896 - interleukin-6 receptor complex
GO:0070301 - cellular response to hydrogen peroxide
GO:0005138 - interleukin-6 receptor binding
GO:0042832 - defense response to protozoan
GO:0050679 - positive regulation of epithelial cell proliferation
GO:0070374 - positive regulation of ERK1 and ERK2 cascade
GO:0042517 - positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0006469 - negative regulation of protein kinase activity
GO:0051971 - positive regulation of transmission of nerve impulse
GO:0005515 - protein binding
GO:0042127 - regulation of cell proliferation
GO:0032722 - positive regulation of chemokine production
GO:0070091 - glucagon secretion
GO:0005576 - extracellular region
GO:0016049 - cell growth
GO:0006955 - immune response
GO:0045893 - positive regulation of transcription, DNA-dependent
GO:0045740 - positive regulation of DNA replication
GO:0005615 - extracellular space
GO:0045454 - cell redox homeostasis
GO:0045188 - regulation of circadian sleep/wake cycle, non-REM sleep
GO:0045768 - positive regulation of anti-apoptosis
GO:0045666 - positive regulation of neuron differentiation
GO:0043154 - negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0051384 - response to glucocorticoid stimulus
GO:0043526 - neuroprotection
GO:0051607 - defense response to virus
GO:0009897 - external side of plasma membrane
GO:0008284 - positive regulation of cell proliferation
GO:0033160 - positive regulation of protein import into nucleus, translocation
GO:0046888 - negative regulation of hormone secretion
GO:0008360 - regulation of cell shape
GO:0002384 - hepatic immune response
GO:0031018 - endocrine pancreas development
GO:0050710 - negative regulation of cytokine secretion
GO:0045721 - negative regulation of gluconeogenesis
GO:0050871 - positive regulation of B cell activation
GO:0042102 - positive regulation of T cell proliferation
GO:0019221 - cytokine-mediated signaling pathway
GO:0045429 - positive regulation of nitric oxide biosynthetic process
GO:0005125 - cytokine activity
GO:0060664 - epithelial cell proliferation involved in salivary gland morphogenesis
GO:0070102 - interleukin-6-mediated signaling pathway
GO:0042110 - T cell activation
GO:0048661 - positive regulation of smooth muscle cell proliferation
GO:0006953 - acute-phase response
GO:0046716 - muscle cell homeostasis
GO:0045079 - negative regulation of chemokine biosynthetic process
GO:0033138 - positive regulation of peptidyl-serine phosphorylation
GO:0051024 - positive regulation of immunoglobulin secretion
GO:0051897 - positive regulation of protein kinase B signaling cascade
GO:0032966 - negative regulation of collagen biosynthetic process
GO:0010574 - regulation of vascular endothelial growth factor production
GO:0046427 - positive regulation of JAK-STAT cascade
GO:0009611 - response to wounding
GO:0008083 - growth factor activity
GO:0043066 - negative regulation of apoptotic process
GO:0060445 - branching involved in salivary gland morphogenesis
GO:0006954 - inflammatory response
GO:0010628 - positive regulation of gene expression
GO:0050731 - positive regulation of peptidyl-tyrosine phosphorylation
GO:0002675 - positive regulation of acute inflammatory response
GO:0048635 - negative regulation of muscle organ development
GO:0031175 - neuron projection development
GO:0045727 - positive regulation of translation
GO:0032755 - positive regulation of interleukin-6 production
GO:0001781 - neutrophil apoptosis
GO:0042981 - regulation of apoptotic process
GO:0008285 - negative regulation of cell proliferation
GO:0005102 - receptor binding
GO:0045944 - positive regulation of transcription from RNA polymerase II promoter
GO:0045630 - positive regulation of T-helper 2 cell differentiation
GO:0043410 - positive regulation of MAPKKK cascade