NIA Mouse Gene Index, mm9

447. U006570
Annotation: cystic fibrosis transmembrane conductance regulator homolog     Gene?: Yes     Source: NM_021050    Symbol:  Cftr
Chromosome: chr6   Strand: +    Start: 18120686    End: 18272769
List: Positive strand of chr6 (N=5540)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR003593 - AAA+ ATPase, core
IPR001140 - ABC transporter, transmembrane region
IPR003439 - ABC transporter related

GO-Ontologies
GO:0043234 - protein complex
GO:0017111 - nucleoside-triphosphatase activity
GO:0030321 - transepithelial chloride transport
GO:0042626 - ATPase activity, coupled to transmembrane movement of substances
GO:0034707 - chloride channel complex
GO:0006833 - water transport
GO:0005737 - cytoplasm
GO:0015701 - bicarbonate transport
GO:0005524 - ATP binding
GO:0005254 - chloride channel activity
GO:0000166 - nucleotide binding
GO:0016021 - integral to membrane
GO:0016020 - membrane
GO:0005902 - microvillus
GO:0005769 - early endosome
GO:0016323 - basolateral plasma membrane
GO:0016887 - ATPase activity
GO:0016324 - apical plasma membrane
GO:0016787 - hydrolase activity
GO:0030301 - cholesterol transport
GO:0042311 - vasodilation
GO:0055085 - transmembrane transport
GO:0005216 - ion channel activity
GO:0005260 - channel-conductance-controlling ATPase activity
GO:0006810 - transport
GO:0030165 - PDZ domain binding
GO:0006821 - chloride transport
GO:0030324 - lung development
GO:0019899 - enzyme binding
GO:0045909 - positive regulation of vasodilation
GO:0005768 - endosome
GO:0006695 - cholesterol biosynthetic process
GO:0006811 - ion transport
GO:0015705 - iodide transport
GO:0030659 - cytoplasmic vesicle membrane