NIA Mouse Gene Index, mm9

754. U006609
Annotation: leptin     Gene?: Yes     Source: NM_008493    Symbol:  Lep
Chromosome: chr6   Strand: +    Start: 29010219    End: 29023877
List: Positive strand of chr6 (N=5540)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR000065 - Obesity factor

GO-Ontologies
GO:0043270 - positive regulation of ion transport
GO:0009892 - negative regulation of metabolic process
GO:0061037 - negative regulation of cartilage development
GO:0007165 - signal transduction
GO:0030073 - insulin secretion
GO:0045639 - positive regulation of myeloid cell differentiation
GO:0042517 - positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0042755 - eating behavior
GO:0042307 - positive regulation of protein import into nucleus
GO:0008203 - cholesterol metabolic process
GO:0005515 - protein binding
GO:0033210 - leptin-mediated signaling pathway
GO:0019222 - regulation of metabolic process
GO:0008206 - bile acid metabolic process
GO:0030300 - regulation of intestinal cholesterol absorption
GO:0045906 - negative regulation of vasoconstriction
GO:0005576 - extracellular region
GO:2000491 - positive regulation of hepatic stellate cell activation
GO:0005615 - extracellular space
GO:0001890 - placenta development
GO:0035630 - bone mineralization involved in bone maturation
GO:0008217 - regulation of blood pressure
GO:0006111 - regulation of gluconeogenesis
GO:0001932 - regulation of protein phosphorylation
GO:0042445 - hormone metabolic process
GO:0032099 - negative regulation of appetite
GO:0050796 - regulation of insulin secretion
GO:0008343 - adult feeding behavior
GO:0070093 - negative regulation of glucagon secretion
GO:0051428 - peptide hormone receptor binding
GO:0046628 - positive regulation of insulin receptor signaling pathway
GO:0005622 - intracellular
GO:0046427 - positive regulation of JAK-STAT cascade
GO:0043066 - negative regulation of apoptotic process
GO:0050810 - regulation of steroid biosynthetic process
GO:0008083 - growth factor activity
GO:0060612 - adipose tissue development
GO:0007260 - tyrosine phosphorylation of STAT protein
GO:0009062 - fatty acid catabolic process
GO:0006629 - lipid metabolic process
GO:0021954 - central nervous system neuron development
GO:2000486 - negative regulation of glutamine transport
GO:0005179 - hormone activity
GO:0060587 - regulation of lipoprotein lipid oxidation
GO:0048639 - positive regulation of developmental growth
GO:0006006 - glucose metabolic process
GO:0050901 - leukocyte tethering or rolling
GO:0008284 - positive regulation of cell proliferation
GO:2000366 - positive regulation of STAT protein import into nucleus
GO:0032868 - response to insulin stimulus
GO:0000122 - negative regulation of transcription from RNA polymerase II promoter
GO:0035556 - intracellular signal transduction
GO:0001542 - ovulation from ovarian follicle
GO:0006112 - energy reserve metabolic process
GO:0006114 - glycerol biosynthetic process
GO:0043410 - positive regulation of MAPKKK cascade
GO:0002021 - response to dietary excess