NIA Mouse Gene Index, mm9

898. U007827
Annotation: transforming growth factor, beta 1     Gene?: Yes     Source: NM_011577    Symbol:  Tgfb1
Chromosome: chr7   Strand: +    Start: 26472020    End: 26490096
List: Positive strand of chr7 (N=5672)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR001111 - Transforming growth factor beta (TGFb), N-terminal
IPR001839 - Transforming growth factor beta

GO-Ontologies
GO:0045662 - negative regulation of myoblast differentiation
GO:0030141 - secretory granule
GO:0010033 - response to organic substance
GO:0030879 - mammary gland development
GO:0050679 - positive regulation of epithelial cell proliferation
GO:0007173 - epidermal growth factor receptor signaling pathway
GO:0001763 - morphogenesis of a branching structure
GO:0071158 - positive regulation of cell cycle arrest
GO:0017015 - regulation of transforming growth factor beta receptor signaling pathway
GO:0022408 - negative regulation of cell-cell adhesion
GO:0031536 - positive regulation of exit from mitosis
GO:0005515 - protein binding
GO:0042127 - regulation of cell proliferation
GO:0050868 - negative regulation of T cell activation
GO:0048642 - negative regulation of skeletal muscle tissue development
GO:0071549 - cellular response to dexamethasone stimulus
GO:0005576 - extracellular region
GO:0035307 - positive regulation of protein dephosphorylation
GO:0045893 - positive regulation of transcription, DNA-dependent
GO:0006796 - phosphate-containing compound metabolic process
GO:0008156 - negative regulation of DNA replication
GO:0045066 - regulatory T cell differentiation
GO:0008354 - germ cell migration
GO:0006874 - cellular calcium ion homeostasis
GO:0032355 - response to estradiol stimulus
GO:0005160 - transforming growth factor beta receptor binding
GO:0005578 - proteinaceous extracellular matrix
GO:0043406 - positive regulation of MAP kinase activity
GO:0006468 - protein phosphorylation
GO:0043552 - positive regulation of phosphatidylinositol 3-kinase activity
GO:0002028 - regulation of sodium ion transport
GO:0002062 - chondrocyte differentiation
GO:0043536 - positive regulation of blood vessel endothelial cell migration
GO:0032740 - positive regulation of interleukin-17 production
GO:0007406 - negative regulation of neuroblast proliferation
GO:0008219 - cell death
GO:0042552 - myelination
GO:0006611 - protein export from nucleus
GO:0007184 - SMAD protein import into nucleus
GO:0032570 - response to progesterone stimulus
GO:0050921 - positive regulation of chemotaxis
GO:0008284 - positive regulation of cell proliferation
GO:0060389 - pathway-restricted SMAD protein phosphorylation
GO:0048535 - lymph node development
GO:0006917 - induction of apoptosis
GO:0030279 - negative regulation of ossification
GO:0051781 - positive regulation of cell division
GO:0042482 - positive regulation of odontogenesis
GO:0045216 - cell-cell junction organization
GO:0051092 - positive regulation of NF-kappaB transcription factor activity
GO:0001933 - negative regulation of protein phosphorylation
GO:0048298 - positive regulation of isotype switching to IgA isotypes
GO:0050680 - negative regulation of epithelial cell proliferation
GO:0090190 - positive regulation of branching involved in ureteric bud morphogenesis
GO:0042110 - T cell activation
GO:0032801 - receptor catabolic process
GO:0007050 - cell cycle arrest
GO:0007183 - SMAD protein complex assembly
GO:0002513 - tolerance induction to self antigen
GO:0050714 - positive regulation of protein secretion
GO:0002244 - hemopoietic progenitor cell differentiation
GO:0043537 - negative regulation of blood vessel endothelial cell migration
GO:0033138 - positive regulation of peptidyl-serine phosphorylation
GO:0009817 - defense response to fungus, incompatible interaction
GO:0051897 - positive regulation of protein kinase B signaling cascade
GO:0060762 - regulation of branching involved in mammary gland duct morphogenesis
GO:0008083 - growth factor activity
GO:0009986 - cell surface
GO:0002460 - adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
GO:0061035 - regulation of cartilage development
GO:0051098 - regulation of binding
GO:0043011 - myeloid dendritic cell differentiation
GO:0060751 - branch elongation involved in mammary gland duct branching
GO:0042060 - wound healing
GO:0000122 - negative regulation of transcription from RNA polymerase II promoter
GO:0031100 - organ regeneration
GO:0043065 - positive regulation of apoptotic process
GO:0045786 - negative regulation of cell cycle
GO:0071363 - cellular response to growth factor stimulus
GO:0045930 - negative regulation of mitotic cell cycle
GO:0019049 - evasion of host defenses by virus
GO:0010763 - positive regulation of fibroblast migration
GO:0032943 - mononuclear cell proliferation
GO:0070723 - response to cholesterol
GO:0007179 - transforming growth factor beta receptor signaling pathway
GO:0007492 - endoderm development
GO:0032270 - positive regulation of cellular protein metabolic process
GO:0035066 - positive regulation of histone acetylation
GO:0050777 - negative regulation of immune response
GO:0050765 - negative regulation of phagocytosis
GO:0016049 - cell growth
GO:0045892 - negative regulation of transcription, DNA-dependent
GO:0005615 - extracellular space
GO:0070306 - lens fiber cell differentiation
GO:0007519 - skeletal muscle tissue development
GO:0010800 - positive regulation of peptidyl-threonine phosphorylation
GO:0051280 - negative regulation of release of sequestered calcium ion into cytosol
GO:0043029 - T cell homeostasis
GO:0008283 - cell proliferation
GO:0030308 - negative regulation of cell growth
GO:0047485 - protein N-terminus binding
GO:0006952 - defense response
GO:0042306 - regulation of protein import into nucleus
GO:0042803 - protein homodimerization activity
GO:0060744 - mammary gland branching involved in thelarche
GO:0051101 - regulation of DNA binding
GO:0001934 - positive regulation of protein phosphorylation
GO:0031065 - positive regulation of histone deacetylation
GO:0031575 - mitotic cell cycle G1/S transition checkpoint
GO:0045599 - negative regulation of fat cell differentiation
GO:0016202 - regulation of striated muscle tissue development
GO:0005737 - cytoplasm
GO:0051152 - positive regulation of smooth muscle cell differentiation
GO:0010862 - positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0043025 - neuronal cell body
GO:0010936 - negative regulation of macrophage cytokine production
GO:0006754 - ATP biosynthetic process
GO:0042130 - negative regulation of T cell proliferation
GO:0000060 - protein import into nucleus, translocation
GO:0040007 - growth
GO:0001837 - epithelial to mesenchymal transition
GO:0032967 - positive regulation of collagen biosynthetic process
GO:0009887 - organ morphogenesis
GO:0006954 - inflammatory response
GO:0010628 - positive regulation of gene expression
GO:0010718 - positive regulation of epithelial to mesenchymal transition
GO:0005114 - type II transforming growth factor beta receptor binding
GO:0031012 - extracellular matrix
GO:0030424 - axon
GO:0008285 - negative regulation of cell proliferation
GO:0001501 - skeletal system development
GO:0005634 - nucleus
GO:0030217 - T cell differentiation
GO:0045944 - positive regulation of transcription from RNA polymerase II promoter
GO:0046982 - protein heterodimerization activity
GO:0060391 - positive regulation of SMAD protein import into nucleus