NIA Mouse Gene Index, mm9

1340. U019374
Annotation: phosphatase and tensin homolog     Gene?: Yes     Source: NM_008960    Symbol:  Pten
Chromosome: chr19   Strand: +    Start: 32831986    End: 32900650
List: Positive strand of chr19 (N=2636)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions

            Similar Genes

Gene
Chr
Strand
Start
N exons
ORF
Symbol
Annotation
U145854
chr3
+
69396515
1
45
  
U357181
chr1
-
97728201
1
43
  (possibly wrong strand)


Exon structure

Domains
IPR000387 - Tyrosine specific protein phosphatase and dual specificity protein phosphatase
IPR003595 - Protein tyrosine phosphatase, catalytic region
IPR000340 - Dual specificity protein phosphatase
IPR008973 - C2 calcium/lipid-binding region, CaLB

GO-Ontologies
GO:0016787 - hydrolase activity
GO:0051898 - negative regulation of protein kinase B signaling cascade
GO:0007507 - heart development
GO:0016791 - phosphoric monoester hydrolase activity
GO:0043066 - negative regulation of apoptosis
GO:0005515 - protein binding
GO:0016311 - dephosphorylation
GO:0048738 - cardiac muscle development
GO:0006470 - protein amino acid dephosphorylation
GO:0008138 - protein tyrosine/serine/threonine phosphatase activity
GO:0001525 - angiogenesis
GO:0008285 - negative regulation of cell proliferation
GO:0006917 - induction of apoptosis
GO:0016314 - phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
GO:0007049 - cell cycle
GO:0043542 - endothelial cell migration
GO:0007417 - central nervous system development
GO:0045786 - negative regulation of cell cycle
GO:0016477 - cell migration