NIA Mouse Gene Index, mm9

5710. U022137
Annotation: presenilin 2     Gene?: Yes     Source: NM_001128605    Symbol:  Psen2
Chromosome: chr1   Strand: -    Start: 182157134    End: 182186431
List: Negative strand of chr1 (N=6229)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR006639 - Peptidase A22, presenilin signal peptide
IPR001108 - Peptidase A22A, presenilin

GO-Ontologies
GO:0005637 - nuclear inner membrane
GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0031594 - neuromuscular junction
GO:0030018 - Z disc
GO:0007176 - regulation of epidermal growth factor-activated receptor activity
GO:0005515 - protein binding
GO:0005624 - membrane fraction
GO:0006915 - apoptotic process
GO:2000059 - negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0016020 - membrane
GO:0042987 - amyloid precursor protein catabolic process
GO:0050435 - beta-amyloid metabolic process
GO:0016324 - apical plasma membrane
GO:0007613 - memory
GO:0016787 - hydrolase activity
GO:0007611 - learning or memory
GO:0005887 - integral to plasma membrane
GO:0043589 - skin morphogenesis
GO:0030900 - forebrain development
GO:0001942 - hair follicle development
GO:0030326 - embryonic limb morphogenesis
GO:0048167 - regulation of synaptic plasticity
GO:0007220 - Notch receptor processing
GO:0044267 - cellular protein metabolic process
GO:0002573 - myeloid leukocyte differentiation
GO:0004175 - endopeptidase activity
GO:0043234 - protein complex
GO:0006508 - proteolysis
GO:0060048 - cardiac muscle contraction
GO:0001933 - negative regulation of protein phosphorylation
GO:0005938 - cell cortex
GO:0048538 - thymus development
GO:0040011 - locomotion
GO:0005794 - Golgi apparatus
GO:0001756 - somitogenesis
GO:0048854 - brain morphogenesis
GO:0048286 - lung alveolus development
GO:0043025 - neuronal cell body
GO:0016021 - integral to membrane
GO:0043085 - positive regulation of catalytic activity
GO:0005765 - lysosomal membrane
GO:0045121 - membrane raft
GO:0002244 - hemopoietic progenitor cell differentiation
GO:0051604 - protein maturation
GO:0007175 - negative regulation of epidermal growth factor-activated receptor activity
GO:0016485 - protein processing
GO:0007219 - Notch signaling pathway
GO:0000776 - kinetochore
GO:0042640 - anagen
GO:0006509 - membrane protein ectodomain proteolysis
GO:0009790 - embryo development
GO:0002286 - T cell activation involved in immune response
GO:0005743 - mitochondrial inner membrane
GO:0030426 - growth cone
GO:0021904 - dorsal/ventral neural tube patterning
GO:0001921 - positive regulation of receptor recycling
GO:0051444 - negative regulation of ubiquitin-protein ligase activity
GO:0001708 - cell fate specification
GO:0043066 - negative regulation of apoptotic process
GO:0043198 - dendritic shaft
GO:0006916 - anti-apoptosis
GO:0009986 - cell surface
GO:0035253 - ciliary rootlet
GO:0048471 - perinuclear region of cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0000122 - negative regulation of transcription from RNA polymerase II promoter
GO:0030424 - axon
GO:0035556 - intracellular signal transduction
GO:0015031 - protein transport
GO:0006816 - calcium ion transport
GO:0004190 - aspartic-type endopeptidase activity
GO:0050820 - positive regulation of coagulation
GO:0005634 - nucleus
GO:0050852 - T cell receptor signaling pathway
GO:0043065 - positive regulation of apoptotic process
GO:0008233 - peptidase activity