NIA Mouse Gene Index, mm9

2037. U024201
Annotation: toll-like receptor 2     Gene?: Yes     Source: NM_011905    Symbol:  Tlr2
Chromosome: chr3   Strand: -    Start: 83640193    End: 83645689
List: Negative strand of chr3 (N=4889)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR003591 - Leucine-rich repeat, typical subtype
IPR000157 - Toll-Interleukin receptor
IPR000483 - Cysteine-rich flanking region, C-terminal

GO-Ontologies
GO:0032760 - positive regulation of tumor necrosis factor production
GO:0071223 - cellular response to lipoteichoic acid
GO:0034123 - positive regulation of toll-like receptor signaling pathway
GO:0008329 - pattern recognition receptor activity
GO:0005515 - protein binding
GO:0032722 - positive regulation of chemokine production
GO:0070891 - lipoteichoic acid binding
GO:0071726 - cellular response to diacyl bacterial lipopeptide
GO:0050830 - defense response to Gram-positive bacterium
GO:0006955 - immune response
GO:0016020 - membrane
GO:0071221 - cellular response to bacterial lipopeptide
GO:0032494 - response to peptidoglycan
GO:0032757 - positive regulation of interleukin-8 production
GO:0042495 - detection of triacyl bacterial lipopeptide
GO:0042346 - positive regulation of NF-kappaB import into nucleus
GO:0031410 - cytoplasmic vesicle
GO:0002687 - positive regulation of leukocyte migration
GO:0002221 - pattern recognition receptor signaling pathway
GO:0005622 - intracellular
GO:0035354 - Toll-like receptor 1-Toll-like receptor 2 protein complex
GO:0009617 - response to bacterium
GO:0002224 - toll-like receptor signaling pathway
GO:0032700 - negative regulation of interleukin-17 production
GO:0051770 - positive regulation of nitric-oxide synthase biosynthetic process
GO:0002282 - microglial cell activation involved in immune response
GO:0042498 - diacyl lipopeptide binding
GO:0051637 - Gram-positive bacterial cell surface binding
GO:0032493 - response to bacterial lipoprotein
GO:0031224 - intrinsic to membrane
GO:0009897 - external side of plasma membrane
GO:0030177 - positive regulation of Wnt receptor signaling pathway
GO:0005886 - plasma membrane
GO:0004872 - receptor activity
GO:0042742 - defense response to bacterium
GO:0007165 - signal transduction
GO:0045429 - positive regulation of nitric oxide biosynthetic process
GO:0044130 - negative regulation of growth of symbiont in host
GO:0005737 - cytoplasm
GO:0042496 - detection of diacyl bacterial lipopeptide
GO:0051092 - positive regulation of NF-kappaB transcription factor activity
GO:0042892 - chloramphenicol transport
GO:0071224 - cellular response to peptidoglycan
GO:0071727 - cellular response to triacyl bacterial lipopeptide
GO:0032728 - positive regulation of interferon-beta production
GO:0052063 - induction by symbiont of defense-related host nitric oxide production
GO:0046209 - nitric oxide metabolic process
GO:0016021 - integral to membrane
GO:0032741 - positive regulation of interleukin-18 production
GO:0002752 - cell surface pattern recognition receptor signaling pathway
GO:0070542 - response to fatty acid
GO:0007252 - I-kappaB phosphorylation
GO:0052033 - pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response
GO:0060907 - positive regulation of macrophage cytokine production
GO:0032735 - positive regulation of interleukin-12 production
GO:0042497 - triacyl lipopeptide binding
GO:0006954 - inflammatory response
GO:0042834 - peptidoglycan binding
GO:0009986 - cell surface
GO:0045087 - innate immune response
GO:0004888 - transmembrane signaling receptor activity
GO:0032755 - positive regulation of interleukin-6 production
GO:0042535 - positive regulation of tumor necrosis factor biosynthetic process
GO:0002238 - response to molecule of fungal origin
GO:0035355 - Toll-like receptor 2-Toll-like receptor 6 protein complex
GO:0002755 - MyD88-dependent toll-like receptor signaling pathway
GO:0032695 - negative regulation of interleukin-12 production
GO:0045944 - positive regulation of transcription from RNA polymerase II promoter
GO:0046982 - protein heterodimerization activity