NIA Mouse Gene Index, mm9

1900. U027382
Annotation: synuclein, alpha     Gene?: Yes     Source: NM_009221    Symbol:  Snca
Chromosome: chr6   Strand: -    Start: 60681565    End: 60779849
List: Negative strand of chr6 (N=5248)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR001058 - Synuclein

GO-Ontologies
GO:0008198 - ferrous iron binding
GO:0005829 - cytosol
GO:0042417 - dopamine metabolic process
GO:0019904 - protein domain specific binding
GO:0015629 - actin cytoskeleton
GO:0043195 - terminal button
GO:0032496 - response to lipopolysaccharide
GO:0005624 - membrane fraction
GO:0031623 - receptor internalization
GO:0048148 - behavioral response to cocaine
GO:0034599 - cellular response to oxidative stress
GO:0006919 - activation of caspase activity
GO:0048169 - regulation of long-term neuronal synaptic plasticity
GO:0043030 - regulation of macrophage activation
GO:0051612 - negative regulation of serotonin uptake
GO:0005509 - calcium ion binding
GO:0050806 - positive regulation of synaptic transmission
GO:0043027 - cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0042393 - histone binding
GO:0060079 - regulation of excitatory postsynaptic membrane potential
GO:0046928 - regulation of neurotransmitter secretion
GO:0043154 - negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006644 - phospholipid metabolic process
GO:0005625 - soluble fraction
GO:0070495 - negative regulation of thrombin receptor signaling pathway
GO:0032026 - response to magnesium ion
GO:0047485 - protein N-terminus binding
GO:0030544 - Hsp70 protein binding
GO:0048488 - synaptic vesicle endocytosis
GO:0032769 - negative regulation of monooxygenase activity
GO:0043524 - negative regulation of neuron apoptosis
GO:0016044 - cellular membrane organization
GO:0008017 - microtubule binding
GO:0060291 - long-term synaptic potentiation
GO:0007006 - mitochondrial membrane organization
GO:0060732 - positive regulation of inositol phosphate biosynthetic process
GO:0043523 - regulation of neuron apoptosis
GO:0005886 - plasma membrane
GO:0010642 - negative regulation of platelet-derived growth factor receptor signaling pathway
GO:0045502 - dynein binding
GO:0006631 - fatty acid metabolic process
GO:0048156 - tau protein binding
GO:0031115 - negative regulation of microtubule polymerization
GO:0014059 - regulation of dopamine secretion
GO:0030659 - cytoplasmic vesicle membrane
GO:0019717 - synaptosome
GO:0051585 - negative regulation of dopamine uptake
GO:0001963 - synaptic transmission, dopaminergic
GO:0001774 - microglial cell activation
GO:0042416 - dopamine biosynthetic process
GO:0051281 - positive regulation of release of sequestered calcium ion into cytosol
GO:0005737 - cytoplasm
GO:0001933 - negative regulation of protein phosphorylation
GO:0005938 - cell cortex
GO:0051219 - phosphoprotein binding
GO:0008344 - adult locomotory behavior
GO:0040012 - regulation of locomotion
GO:0042802 - identical protein binding
GO:0042775 - mitochondrial ATP synthesis coupled electron transport
GO:0043014 - alpha-tubulin binding
GO:0043274 - phospholipase binding
GO:0019894 - kinesin binding
GO:0050544 - arachidonic acid binding
GO:0071902 - positive regulation of protein serine/threonine kinase activity
GO:0070555 - response to interleukin-1
GO:0033138 - positive regulation of peptidyl-serine phosphorylation
GO:0034341 - response to interferon-gamma
GO:0043205 - fibril
GO:0000287 - magnesium ion binding
GO:0035067 - negative regulation of histone acetylation
GO:0030426 - growth cone
GO:0001921 - positive regulation of receptor recycling
GO:0005543 - phospholipid binding
GO:0048489 - synaptic vesicle transport
GO:0006916 - anti-apoptosis
GO:0006638 - neutral lipid metabolic process
GO:0032410 - negative regulation of transporter activity
GO:0005856 - cytoskeleton
GO:0045807 - positive regulation of endocytosis
GO:0048168 - regulation of neuronal synaptic plasticity
GO:0045963 - negative regulation of dopamine metabolic process
GO:0051622 - negative regulation of norepinephrine uptake
GO:0043679 - axon terminus
GO:0008270 - zinc ion binding
GO:0019899 - enzyme binding
GO:0010040 - response to iron(II) ion
GO:0005792 - microsome
GO:0042493 - response to drug
GO:0030424 - axon
GO:0005739 - mitochondrion
GO:0045920 - negative regulation of exocytosis
GO:0010517 - regulation of phospholipase activity
GO:0005634 - nucleus
GO:0001956 - positive regulation of neurotransmitter secretion
GO:0050812 - regulation of acyl-CoA biosynthetic process
GO:0014048 - regulation of glutamate secretion
GO:0008021 - synaptic vesicle