NIA Mouse Gene Index, mm9

621. U028237
Annotation: apolipoprotein E     Gene?: Yes     Source: NM_009696    Symbol:  Apoe
Chromosome: chr7   Strand: -    Start: 20281592    End: 20284515
List: Negative strand of chr7 (N=5573)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR000074 - Apolipoprotein A1/A4/E

GO-Ontologies
GO:0006869 - lipid transport
GO:0034375 - high-density lipoprotein particle remodeling
GO:0001540 - beta-amyloid binding
GO:0008104 - protein localization
GO:0005576 - extracellular region
GO:0019934 - cGMP-mediated signaling
GO:0010544 - negative regulation of platelet activation
GO:0006898 - receptor-mediated endocytosis
GO:0030195 - negative regulation of blood coagulation
GO:0005615 - extracellular space
GO:0031103 - axon regeneration
GO:0007568 - aging
GO:0005769 - early endosome
GO:0072358 - cardiovascular system development
GO:0005770 - late endosome
GO:0006874 - cellular calcium ion homeostasis
GO:0034362 - low-density lipoprotein particle
GO:0051000 - positive regulation of nitric-oxide synthase activity
GO:0042311 - vasodilation
GO:0005874 - microtubule
GO:0071813 - lipoprotein particle binding
GO:0034382 - chylomicron remnant clearance
GO:0042157 - lipoprotein metabolic process
GO:0051651 - maintenance of location in cell
GO:0043691 - reverse cholesterol transport
GO:0034364 - high-density lipoprotein particle
GO:0006810 - transport
GO:0017127 - cholesterol transporter activity
GO:0042803 - protein homodimerization activity
GO:0070326 - very-low-density lipoprotein particle receptor binding
GO:0045471 - response to ethanol
GO:0006707 - cholesterol catabolic process
GO:0031232 - extrinsic to external side of plasma membrane
GO:0048156 - tau protein binding
GO:0042627 - chylomicron
GO:0006917 - induction of apoptosis
GO:0033344 - cholesterol efflux
GO:0006979 - response to oxidative stress
GO:0002021 - response to dietary excess
GO:0016209 - antioxidant activity
GO:0032805 - positive regulation of low-density lipoprotein particle receptor catabolic process
GO:0007263 - nitric oxide mediated signal transduction
GO:0001937 - negative regulation of endothelial cell proliferation
GO:0034374 - low-density lipoprotein particle remodeling
GO:0034384 - high-density lipoprotein particle clearance
GO:0048844 - artery morphogenesis
GO:0005737 - cytoplasm
GO:0046911 - metal chelating activity
GO:0008203 - cholesterol metabolic process
GO:0050750 - low-density lipoprotein particle receptor binding
GO:0005794 - Golgi apparatus
GO:0005319 - lipid transporter activity
GO:0032488 - Cdc42 protein signal transduction
GO:0042158 - lipoprotein biosynthetic process
GO:0043025 - neuronal cell body
GO:0042802 - identical protein binding
GO:0043085 - positive regulation of catalytic activity
GO:0042159 - lipoprotein catabolic process
GO:0034361 - very-low-density lipoprotein particle
GO:0043407 - negative regulation of MAP kinase activity
GO:0045541 - negative regulation of cholesterol biosynthetic process
GO:0043537 - negative regulation of blood vessel endothelial cell migration
GO:0034447 - very-low-density lipoprotein particle clearance
GO:0030828 - positive regulation of cGMP biosynthetic process
GO:0008289 - lipid binding
GO:0060228 - phosphatidylcholine-sterol O-acyltransferase activator activity
GO:0007186 - G-protein coupled receptor signaling pathway
GO:0034372 - very-low-density lipoprotein particle remodeling
GO:0005543 - phospholipid binding
GO:0034363 - intermediate-density lipoprotein particle
GO:0006916 - anti-apoptosis
GO:0030425 - dendrite
GO:0006629 - lipid metabolic process
GO:0008201 - heparin binding
GO:0055088 - lipid homeostasis
GO:0010875 - positive regulation of cholesterol efflux
GO:0033700 - phospholipid efflux
GO:0006641 - triglyceride metabolic process
GO:0034380 - high-density lipoprotein particle assembly
GO:0042632 - cholesterol homeostasis
GO:0051044 - positive regulation of membrane protein ectodomain proteolysis
GO:0046982 - protein heterodimerization activity
GO:0010873 - positive regulation of cholesterol esterification
GO:0010468 - regulation of gene expression