NIA Mouse Gene Index, mm9

3. U029533
Annotation: insulin receptor     Gene?: Yes     Source: NM_010568    Symbol:  Insr
Chromosome: chr8   Strand: -    Start: 3122060    End: 3279617
List: Negative strand of chr8 (N=4537)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR002290 - Serine/threonine protein kinase
IPR003961 - Fibronectin, type III
IPR000494 - EGF receptor, L domain
IPR006212 - Furin-like repeat
IPR006211 - Furin-like cysteine rich region
IPR000719 - Protein kinase, core
IPR001245 - Tyrosine protein kinase

GO-Ontologies
GO:0071363 - cellular response to growth factor stimulus
GO:0030238 - male sex determination
GO:0032147 - activation of protein kinase activity
GO:0004672 - protein kinase activity
GO:0003007 - heart morphogenesis
GO:0005829 - cytosol
GO:0008286 - insulin receptor signaling pathway
GO:0019904 - protein domain specific binding
GO:0005515 - protein binding
GO:0004716 - receptor signaling protein tyrosine kinase activity
GO:0000166 - nucleotide binding
GO:0016301 - kinase activity
GO:0030335 - positive regulation of cell migration
GO:0032148 - activation of protein kinase B activity
GO:0031017 - exocrine pancreas development
GO:0045740 - positive regulation of DNA replication
GO:0016020 - membrane
GO:0045995 - regulation of embryonic development
GO:0000187 - activation of MAPK activity
GO:0034612 - response to tumor necrosis factor
GO:0006355 - regulation of transcription, DNA-dependent
GO:0005625 - soluble fraction
GO:0005159 - insulin-like growth factor receptor binding
GO:0005009 - insulin-activated receptor activity
GO:0006468 - protein phosphorylation
GO:0018108 - peptidyl-tyrosine phosphorylation
GO:0005887 - integral to plasma membrane
GO:0045821 - positive regulation of glycolysis
GO:0016310 - phosphorylation
GO:0046326 - positive regulation of glucose import
GO:0042169 - SH2 domain binding
GO:0005901 - caveola
GO:0010310 - regulation of hydrogen peroxide metabolic process
GO:0008284 - positive regulation of cell proliferation
GO:0005886 - plasma membrane
GO:0007169 - transmembrane receptor protein tyrosine kinase signaling pathway
GO:0045725 - positive regulation of glycogen biosynthetic process
GO:0001934 - positive regulation of protein phosphorylation
GO:0004872 - receptor activity
GO:0032869 - cellular response to insulin stimulus
GO:0031405 - lipoic acid binding
GO:0043423 - 3-phosphoinositide-dependent protein kinase binding
GO:0045429 - positive regulation of nitric oxide biosynthetic process
GO:0060267 - positive regulation of respiratory burst
GO:0010560 - positive regulation of glycoprotein biosynthetic process
GO:0043548 - phosphatidylinositol 3-kinase binding
GO:0005524 - ATP binding
GO:0001933 - negative regulation of protein phosphorylation
GO:0043559 - insulin binding
GO:0042327 - positive regulation of phosphorylation
GO:0005899 - insulin receptor complex
GO:0016021 - integral to membrane
GO:0031994 - insulin-like growth factor I binding
GO:0051290 - protein heterotetramerization
GO:0016772 - transferase activity, transferring phosphorus-containing groups
GO:0016740 - transferase activity
GO:0032403 - protein complex binding
GO:0046777 - protein autophosphorylation
GO:0042593 - glucose homeostasis
GO:0051425 - PTB domain binding
GO:0051897 - positive regulation of protein kinase B signaling cascade
GO:0007186 - G-protein coupled receptor signaling pathway
GO:0009887 - organ morphogenesis
GO:0032410 - negative regulation of transporter activity
GO:0046872 - metal ion binding
GO:0043560 - insulin receptor substrate binding
GO:0019903 - protein phosphatase binding
GO:0004714 - transmembrane receptor protein tyrosine kinase activity
GO:0031995 - insulin-like growth factor II binding
GO:0048639 - positive regulation of developmental growth
GO:0005525 - GTP binding
GO:0004713 - protein tyrosine kinase activity
GO:0005792 - microsome
GO:0045840 - positive regulation of mitosis
GO:0010629 - negative regulation of gene expression
GO:0005768 - endosome
GO:0019901 - protein kinase binding
GO:0005634 - nucleus
GO:0019087 - transformation of host cell by virus
GO:0043410 - positive regulation of MAPKKK cascade
GO:0045202 - synapse