NIA Mouse Gene Index, mm9

2464. U030990
Annotation: MAD homolog 3 (Drosophila)     Gene?: Yes     Source: NM_016769    Symbol:  Smad3
Chromosome: chr9   Strand: -    Start: 63494572    End: 63605944
List: Negative strand of chr9 (N=4994)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR001132 - MAD homology 2, Dwarfin-type
IPR003619 - MAD homology 1, Dwarfin-type

GO-Ontologies
GO:0008134 - transcription factor binding
GO:0045930 - negative regulation of mitotic cell cycle
GO:0005637 - nuclear inner membrane
GO:0019049 - evasion of host defenses by virus
GO:0001889 - liver development
GO:0050728 - negative regulation of inflammatory response
GO:0043235 - receptor complex
GO:0017015 - regulation of transforming growth factor beta receptor signaling pathway
GO:0003677 - DNA binding
GO:0009880 - embryonic pattern specification
GO:0045668 - negative regulation of osteoblast differentiation
GO:0007179 - transforming growth factor beta receptor signaling pathway
GO:0007492 - endoderm development
GO:0005515 - protein binding
GO:0030501 - positive regulation of bone mineralization
GO:0005667 - transcription factor complex
GO:0010694 - positive regulation of alkaline phosphatase activity
GO:0001707 - mesoderm formation
GO:0003690 - double-stranded DNA binding
GO:0019902 - phosphatase binding
GO:0048701 - embryonic cranial skeleton morphogenesis
GO:0006919 - activation of caspase activity
GO:0030335 - positive regulation of cell migration
GO:0006955 - immune response
GO:0045893 - positive regulation of transcription, DNA-dependent
GO:0090263 - positive regulation of canonical Wnt receptor signaling pathway
GO:0035413 - positive regulation of catenin import into nucleus
GO:0001947 - heart looping
GO:0070306 - lens fiber cell differentiation
GO:0050927 - positive regulation of positive chemotaxis
GO:0001102 - RNA polymerase II activating transcription factor binding
GO:0006355 - regulation of transcription, DNA-dependent
GO:0005160 - transforming growth factor beta receptor binding
GO:0050776 - regulation of immune response
GO:0003700 - sequence-specific DNA binding transcription factor activity
GO:0005622 - intracellular
GO:0030308 - negative regulation of cell growth
GO:0048340 - paraxial mesoderm morphogenesis
GO:0000987 - core promoter proximal region sequence-specific DNA binding
GO:0005518 - collagen binding
GO:0033689 - negative regulation of osteoblast proliferation
GO:0008637 - apoptotic mitochondrial changes
GO:0046332 - SMAD binding
GO:0006810 - transport
GO:0032731 - positive regulation of interleukin-1 beta production
GO:0060039 - pericardium development
GO:0043130 - ubiquitin binding
GO:0048617 - embryonic foregut morphogenesis
GO:0042803 - protein homodimerization activity
GO:0048589 - developmental growth
GO:0042993 - positive regulation of transcription factor import into nucleus
GO:0005886 - plasma membrane
GO:0001649 - osteoblast differentiation
GO:0070412 - R-SMAD binding
GO:0006917 - induction of apoptosis
GO:0061045 - negative regulation of wound healing
GO:0043234 - protein complex
GO:0051894 - positive regulation of focal adhesion assembly
GO:0031625 - ubiquitin protein ligase binding
GO:0002076 - osteoblast development
GO:0045216 - cell-cell junction organization
GO:0006366 - transcription from RNA polymerase II promoter
GO:0016202 - regulation of striated muscle tissue development
GO:0005737 - cytoplasm
GO:0060290 - transdifferentiation
GO:0070410 - co-SMAD binding
GO:0001933 - negative regulation of protein phosphorylation
GO:0042110 - T cell activation
GO:0044212 - transcription regulatory region DNA binding
GO:0001756 - somitogenesis
GO:0071141 - SMAD protein complex
GO:0007050 - cell cycle arrest
GO:0001666 - response to hypoxia
GO:0007183 - SMAD protein complex assembly
GO:0006351 - transcription, DNA-dependent
GO:0042177 - negative regulation of protein catabolic process
GO:0043565 - sequence-specific DNA binding
GO:0002520 - immune system development
GO:0008013 - beta-catenin binding
GO:0030878 - thyroid gland development
GO:0032916 - positive regulation of transforming growth factor beta3 production
GO:0043066 - negative regulation of apoptotic process
GO:0051496 - positive regulation of stress fiber assembly
GO:0050678 - regulation of epithelial cell proliferation
GO:0046872 - metal ion binding
GO:0001836 - release of cytochrome c from mitochondria
GO:0010718 - positive regulation of epithelial to mesenchymal transition
GO:0032332 - positive regulation of chondrocyte differentiation
GO:0030618 - transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031490 - chromatin DNA binding
GO:0001701 - in utero embryonic development
GO:0008270 - zinc ion binding
GO:0051098 - regulation of binding
GO:0008633 - activation of pro-apoptotic gene products
GO:0000122 - negative regulation of transcription from RNA polymerase II promoter
GO:0001501 - skeletal system development
GO:0008285 - negative regulation of cell proliferation
GO:0005634 - nucleus
GO:0019901 - protein kinase binding
GO:0007369 - gastrulation
GO:0003682 - chromatin binding
GO:0050821 - protein stabilization
GO:0045944 - positive regulation of transcription from RNA polymerase II promoter
GO:0032909 - regulation of transforming growth factor beta2 production
GO:0003706 - ligand-regulated transcription factor activity