NIA Mouse Gene Index, mm9

3942. U032277
Annotation: interleukin-1 receptor-associated kinase 3     Gene?: Yes     Source: NM_028679    Symbol:  Irak3
Chromosome: chr10   Strand: -    Start: 119578703    End: 119639186
List: Negative strand of chr10 (N=4396)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR002290 - Serine/threonine protein kinase
IPR000488 - Death
IPR011019 - KIND
IPR000219 - DH
IPR000719 - Protein kinase, core
IPR001245 - Tyrosine protein kinase

GO-Ontologies
GO:0019221 - cytokine-mediated signaling pathway
GO:0043330 - response to exogenous dsRNA
GO:0007165 - signal transduction
GO:0004672 - protein kinase activity
GO:0010933 - positive regulation of macrophage tolerance induction
GO:0005737 - cytoplasm
GO:0009615 - response to virus
GO:0051092 - positive regulation of NF-kappaB transcription factor activity
GO:0005524 - ATP binding
GO:0032496 - response to lipopolysaccharide
GO:0000166 - nucleotide binding
GO:0016301 - kinase activity
GO:0006915 - apoptotic process
GO:0043242 - negative regulation of protein complex disassembly
GO:0070498 - interleukin-1-mediated signaling pathway
GO:0010936 - negative regulation of macrophage cytokine production
GO:0043407 - negative regulation of MAP kinase activity
GO:0032715 - negative regulation of interleukin-6 production
GO:0042177 - negative regulation of protein catabolic process
GO:0032494 - response to peptidoglycan
GO:0070555 - response to interleukin-1
GO:0016772 - transferase activity, transferring phosphorus-containing groups
GO:0016740 - transferase activity
GO:0034122 - negative regulation of toll-like receptor signaling pathway
GO:0046777 - protein autophosphorylation
GO:0004674 - protein serine/threonine kinase activity
GO:0045824 - negative regulation of innate immune response
GO:0032720 - negative regulation of tumor necrosis factor production
GO:0006468 - protein phosphorylation
GO:0000287 - magnesium ion binding
GO:0016310 - phosphorylation
GO:0043244 - regulation of protein complex disassembly
GO:0042803 - protein homodimerization activity
GO:0032695 - negative regulation of interleukin-12 production
GO:0042981 - regulation of apoptotic process
GO:0005634 - nucleus
GO:0001960 - negative regulation of cytokine-mediated signaling pathway
GO:0046982 - protein heterodimerization activity
GO:0032088 - negative regulation of NF-kappaB transcription factor activity
GO:0004872 - receptor activity