NIA Mouse Gene Index, mm9

2804. U037244
Annotation: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)     Gene?: Yes     Source: NM_011782    Symbol:  Adamts5
Chromosome: chr16   Strand: -    Start: 85858070    End: 85901370
List: Negative strand of chr16 (N=3333)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions

Exon structure

IPR002870 - Peptidase M12B, propeptide
IPR000884 - Thrombospondin, type I
IPR006026 - Peptidase, metallopeptidases
IPR006586 - ADAM, cysteine-rich
IPR001590 - Peptidase M12B, ADAM/reprolysin
IPR010294 - ADAM-TS Spacer 1
IPR001818 - Peptidase M10A and M12B, matrixin and adamalysin

GO:0008237 - metallopeptidase activity
GO:0005576 - extracellular region
GO:0006508 - proteolysis
GO:0016787 - hydrolase activity
GO:0031012 - extracellular matrix
GO:0008270 - zinc ion binding
GO:0046872 - metal ion binding
GO:0008152 - metabolic process
GO:0008233 - peptidase activity
GO:0004222 - metalloendopeptidase activity
GO:0005578 - proteinaceous extracellular matrix