NIA Mouse Gene Index, mm9

2655. U037244
Annotation: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)     Gene?: Yes     Source: NM_011782    Symbol:  Adamts5
Chromosome: chr16   Strand: -    Start: 85858070    End: 85901370
List: Negative strand of chr16 (N=3156)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions

            Similar Genes

Gene
Chr
Strand
Start
N exons
ORF
Symbol
Annotation
U088892
chr5
+
54195102
1
0
 Copy of A0817E11-5 NIA Mouse E13.5 whole embryo cDNA library (Long) Mus musculus cDNA clone NIA:A0817E11 IMAGE:30758842 5', mRNA sequence


Exon structure

Domains
IPR013273 - ADAM-TS
IPR002870 - Peptidase M12B, propeptide
IPR000884 - Thrombospondin, type I
IPR001590 - Peptidase M12B, ADAM/reprolysin
IPR006025 - Peptidase M, neutral zinc metallopeptidases, zinc-binding site
IPR013276 - ADAM-TS5
IPR006586 - ADAM, cysteine-rich
IPR010294 - ADAM-TS Spacer 1

GO-Ontologies
GO:0008237 - metallopeptidase activity
GO:0005576 - extracellular region
GO:0006508 - proteolysis
GO:0016787 - hydrolase activity
GO:0031012 - extracellular matrix
GO:0008270 - zinc ion binding
GO:0007229 - integrin-mediated signaling pathway
GO:0046872 - metal ion binding
GO:0004222 - metalloendopeptidase activity
GO:0008233 - peptidase activity
GO:0005578 - proteinaceous extracellular matrix