NIA Mouse Gene Index, mm9

1659. U037744
Annotation: tumor necrosis factor     Gene?: Yes     Source: NM_013693    Symbol:  Tnf
Chromosome: chr17   Strand: -    Start: 35336317    End: 35338952
List: Negative strand of chr17 (N=3764)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR002959 - Tumour necrosis factor alpha/cachectin
IPR003636 - Tumour necrosis factor subfamily
IPR008983 - TNF-like
IPR006053 - Tumor necrosis factor alpha, beta and c
IPR006052 - Tumor Necrosis Factor

GO-Ontologies
GO:0042742 - defense response to bacterium
GO:0030141 - secretory granule
GO:0046325 - negative regulation of glucose import
GO:0005125 - cytokine activity
GO:0007254 - JNK cascade
GO:0005515 - protein binding
GO:0042127 - regulation of cell proliferation
GO:0051798 - positive regulation of hair follicle development
GO:0005576 - extracellular region
GO:0006955 - immune response
GO:0016021 - integral to membrane
GO:0051092 - activation of NF-kappaB transcription factor
GO:0005615 - extracellular space
GO:0005164 - tumor necrosis factor receptor binding
GO:0016020 - membrane
GO:0006927 - transformed cell apoptosis
GO:0008624 - induction of apoptosis by extracellular signals
GO:0008283 - cell proliferation
GO:0045994 - positive regulation of translational initiation by iron
GO:0043123 - positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0045941 - positive regulation of transcription
GO:0046330 - positive regulation of JNK cascade
GO:0006954 - inflammatory response
GO:0045123 - cellular extravasation
GO:0009887 - organ morphogenesis
GO:0005887 - integral to plasma membrane
GO:0006959 - humoral immune response
GO:0006952 - defense response
GO:0001891 - phagocytic cup
GO:0008625 - induction of apoptosis via death domain receptors
GO:0001932 - regulation of protein amino acid phosphorylation
GO:0055037 - recycling endosome
GO:0009897 - external side of plasma membrane
GO:0007275 - multicellular organismal development
GO:0006006 - glucose metabolic process
GO:0045670 - regulation of osteoclast differentiation
GO:0008284 - positive regulation of cell proliferation
GO:0051023 - regulation of immunoglobulin secretion
GO:0005886 - plasma membrane
GO:0000122 - negative regulation of transcription from RNA polymerase II promoter
GO:0006917 - induction of apoptosis
GO:0030316 - osteoclast differentiation
GO:0050900 - leukocyte migration
GO:0045944 - positive regulation of transcription from RNA polymerase II promoter