NIA Mouse Gene Index, mm9

2278. U038549
Annotation: MAD homolog 4 (Drosophila)     Gene?: Yes     Source: NM_008540    Symbol:  Smad4
Chromosome: chr18   Strand: -    Start: 73798387    End: 73863434
List: Negative strand of chr18 (N=2823)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR008781 - Pneumovirinae attachment membrane glycoprotein G
IPR001132 - MAD homology 2, Dwarfin-type
IPR003619 - MAD homology 1, Dwarfin-type

GO-Ontologies
GO:0014033 - neural crest cell differentiation
GO:0001658 - branching involved in ureteric bud morphogenesis
GO:0017015 - regulation of transforming growth factor beta receptor signaling pathway
GO:0005813 - centrosome
GO:0051797 - regulation of hair follicle development
GO:0072133 - metanephric mesenchyme morphogenesis
GO:0003677 - DNA binding
GO:0007179 - transforming growth factor beta receptor signaling pathway
GO:0007492 - endoderm development
GO:0005515 - protein binding
GO:0042127 - regulation of cell proliferation
GO:0005667 - transcription factor complex
GO:0007498 - mesoderm development
GO:0048859 - formation of anatomical boundary
GO:0045893 - positive regulation of transcription, DNA-dependent
GO:0045892 - negative regulation of transcription, DNA-dependent
GO:0048733 - sebaceous gland development
GO:0072134 - nephrogenic mesenchyme morphogenesis
GO:0006355 - regulation of transcription, DNA-dependent
GO:0008283 - cell proliferation
GO:0003700 - sequence-specific DNA binding transcription factor activity
GO:0005622 - intracellular
GO:0030308 - negative regulation of cell growth
GO:0070411 - I-SMAD binding
GO:0032525 - somite rostral/caudal axis specification
GO:0030509 - BMP signaling pathway
GO:0000987 - core promoter proximal region sequence-specific DNA binding
GO:0005518 - collagen binding
GO:0046332 - SMAD binding
GO:0048729 - tissue morphogenesis
GO:0006357 - regulation of transcription from RNA polymerase II promoter
GO:0071559 - response to transforming growth factor beta stimulus
GO:0042803 - protein homodimerization activity
GO:0048589 - developmental growth
GO:0070412 - R-SMAD binding
GO:0032444 - activin responsive factor complex
GO:0043234 - protein complex
GO:0060021 - palate development
GO:0005737 - cytoplasm
GO:0048663 - neuron fate commitment
GO:0010862 - positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0044212 - transcription regulatory region DNA binding
GO:0060395 - SMAD protein signal transduction
GO:0071141 - SMAD protein complex
GO:0042802 - identical protein binding
GO:0001666 - response to hypoxia
GO:0007183 - SMAD protein complex assembly
GO:0060548 - negative regulation of cell death
GO:0042177 - negative regulation of protein catabolic process
GO:0006351 - transcription, DNA-dependent
GO:0001702 - gastrulation with mouth forming second
GO:0030511 - positive regulation of transforming growth factor beta receptor signaling pathway
GO:0009952 - anterior/posterior pattern specification
GO:0010718 - positive regulation of epithelial to mesenchymal transition
GO:0001701 - in utero embryonic development
GO:0001822 - kidney development
GO:0030616 - transforming growth factor beta receptor, common-partner cytoplasmic mediator activity
GO:0051098 - regulation of binding
GO:0008285 - negative regulation of cell proliferation
GO:0005634 - nucleus
GO:0007369 - gastrulation
GO:0003682 - chromatin binding
GO:0045944 - positive regulation of transcription from RNA polymerase II promoter
GO:0032909 - regulation of transforming growth factor beta2 production
GO:0060391 - positive regulation of SMAD protein import into nucleus