NIA Mouse Gene Index, mm9

4649. U042686
Annotation: purinergic receptor P2X, ligand-gated ion channel, 7     Gene?: Yes     Source: NM_001038845    Symbol:  P2rx7
Chromosome: chr5   Strand: +    Start: 123093919    End: 123141441
List: Positive strand of chr5 (N=6089)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR001429 - P2X purinoreceptor

GO-Ontologies
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0033198 - response to ATP
GO:0010033 - response to organic substance
GO:0045332 - phospholipid translocation
GO:0006884 - cell volume homeostasis
GO:0034405 - response to fluid shear stress
GO:0051901 - positive regulation of mitochondrial depolarization
GO:0031594 - neuromuscular junction
GO:0019835 - cytolysis
GO:0005515 - protein binding
GO:0043195 - terminal button
GO:0007005 - mitochondrion organization
GO:0030501 - positive regulation of bone mineralization
GO:0032496 - response to lipopolysaccharide
GO:0000902 - cell morphogenesis
GO:0051899 - membrane depolarization
GO:0045779 - negative regulation of bone resorption
GO:0051259 - protein oligomerization
GO:0001614 - purinergic nucleotide receptor activity
GO:0019233 - sensory perception of pain
GO:0050830 - defense response to Gram-positive bacterium
GO:0005911 - cell-cell junction
GO:0016020 - membrane
GO:0051209 - release of sequestered calcium ion into cytosol
GO:0000187 - activation of MAPK activity
GO:0048705 - skeletal system morphogenesis
GO:0032060 - bleb assembly
GO:0034220 - ion transmembrane transport
GO:0032059 - bleb
GO:0032308 - positive regulation of prostaglandin secretion
GO:0007166 - cell surface receptor linked signaling pathway
GO:0043029 - T cell homeostasis
GO:0006468 - protein phosphorylation
GO:0002028 - regulation of sodium ion transport
GO:0055085 - transmembrane transport
GO:0009617 - response to bacterium
GO:0005887 - integral to plasma membrane
GO:0008219 - cell death
GO:0050718 - positive regulation of interleukin-1 beta secretion
GO:0006810 - transport
GO:0032731 - positive regulation of interleukin-1 beta production
GO:0043132 - NAD transport
GO:0010467 - gene expression
GO:0001845 - phagolysosome assembly
GO:0009897 - external side of plasma membrane
GO:0042098 - T cell proliferation
GO:0004931 - extracellular ATP-gated cation channel activity
GO:0072593 - reactive oxygen species metabolic process
GO:0048873 - homeostasis of number of cells within a tissue
GO:0005886 - plasma membrane
GO:0001934 - positive regulation of protein phosphorylation
GO:0004872 - receptor activity
GO:0006811 - ion transport
GO:0019717 - synaptosome
GO:0043539 - protein serine/threonine kinase activator activity
GO:0043234 - protein complex
GO:0046513 - ceramide biosynthetic process
GO:0005737 - cytoplasm
GO:0005524 - ATP binding
GO:0006812 - cation transport
GO:0007009 - plasma membrane organization
GO:0035590 - purinergic nucleotide receptor signaling pathway
GO:0006649 - phospholipid transfer to membrane
GO:0032963 - collagen metabolic process
GO:0043025 - neuronal cell body
GO:0045778 - positive regulation of ossification
GO:0016021 - integral to membrane
GO:0043085 - positive regulation of catalytic activity
GO:0045121 - membrane raft
GO:0006900 - membrane budding
GO:0050714 - positive regulation of protein secretion
GO:0071902 - positive regulation of protein serine/threonine kinase activity
GO:0001530 - lipopolysaccharide binding
GO:0051495 - positive regulation of cytoskeleton organization
GO:0016485 - protein processing
GO:0016079 - synaptic vesicle exocytosis
GO:0015267 - channel activity
GO:0006509 - membrane protein ectodomain proteolysis
GO:0050715 - positive regulation of cytokine secretion
GO:0000287 - magnesium ion binding
GO:0050717 - positive regulation of interleukin-1 alpha secretion
GO:0051592 - response to calcium ion
GO:0097110 - scaffold protein binding
GO:0045919 - positive regulation of cytolysis
GO:0006954 - inflammatory response
GO:0005639 - integral to nuclear inner membrane
GO:0005216 - ion channel activity
GO:0044254 - multicellular organismal protein catabolic process
GO:0005507 - copper ion binding
GO:0014070 - response to organic cyclic compound
GO:0010043 - response to zinc ion
GO:0010524 - positive regulation of calcium ion transport into cytosol
GO:0051602 - response to electrical stimulus
GO:0032755 - positive regulation of interleukin-6 production
GO:0008270 - zinc ion binding
GO:0009612 - response to mechanical stimulus
GO:0014049 - positive regulation of glutamate secretion
GO:0042493 - response to drug
GO:0046931 - pore complex assembly
GO:0006816 - calcium ion transport
GO:0042981 - regulation of apoptotic process
GO:0031668 - cellular response to extracellular stimulus
GO:0005102 - receptor binding
GO:0019228 - regulation of action potential in neuron
GO:0043409 - negative regulation of MAPKKK cascade
GO:0043065 - positive regulation of apoptotic process
GO:0043410 - positive regulation of MAPKKK cascade
GO:0014054 - positive regulation of gamma-aminobutyric acid secretion