NIA Mouse Gene Index, mm9

739. U042893
Annotation: secreted frizzled-related protein 1     Gene?: Yes     Source: NM_013834    Symbol:  Sfrp1
Chromosome: chr8   Strand: +    Start: 24521778    End: 24560104
List: Positive strand of chr8 (N=4730)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR001134 - Netrin, C-terminal
IPR000024 - Frizzled CRD region

GO-Ontologies
GO:0071363 - cellular response to growth factor stimulus
GO:0050679 - positive regulation of epithelial cell proliferation
GO:0005829 - cytosol
GO:0010564 - regulation of cell cycle process
GO:0045668 - negative regulation of osteoblast differentiation
GO:0045600 - positive regulation of fat cell differentiation
GO:0030307 - positive regulation of cell growth
GO:0004197 - cysteine-type endopeptidase activity
GO:0005576 - extracellular region
GO:0008144 - drug binding
GO:0045892 - negative regulation of transcription, DNA-dependent
GO:0045893 - positive regulation of transcription, DNA-dependent
GO:0005615 - extracellular space
GO:0090263 - positive regulation of canonical Wnt receptor signaling pathway
GO:0010719 - negative regulation of epithelial to mesenchymal transition
GO:0006309 - DNA fragmentation involved in apoptotic nuclear change
GO:0046546 - development of primary male sexual characteristics
GO:0071356 - cellular response to tumor necrosis factor
GO:2000080 - negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation
GO:0060766 - negative regulation of androgen receptor signaling pathway
GO:0005578 - proteinaceous extracellular matrix
GO:0071504 - cellular response to heparin
GO:0030178 - negative regulation of Wnt receptor signaling pathway
GO:0005622 - intracellular
GO:0060687 - regulation of branching involved in prostate gland morphogenesis
GO:0030308 - negative regulation of cell growth
GO:0021915 - neural tube development
GO:2000041 - negative regulation of planar cell polarity pathway involved in axis elongation
GO:0033689 - negative regulation of osteoblast proliferation
GO:0009950 - dorsal/ventral axis specification
GO:0060527 - prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0030165 - PDZ domain binding
GO:2000052 - positive regulation of non-canonical Wnt receptor signaling pathway
GO:0050732 - negative regulation of peptidyl-tyrosine phosphorylation
GO:0006357 - regulation of transcription from RNA polymerase II promoter
GO:0045578 - negative regulation of B cell differentiation
GO:0030278 - regulation of ossification
GO:0090179 - planar cell polarity pathway involved in neural tube closure
GO:0008284 - positive regulation of cell proliferation
GO:0030177 - positive regulation of Wnt receptor signaling pathway
GO:0005886 - plasma membrane
GO:0001843 - neural tube closure
GO:2000270 - negative regulation of fibroblast apoptosis
GO:2000054 - negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification
GO:0044344 - cellular response to fibroblast growth factor stimulus
GO:0016055 - Wnt receptor signaling pathway
GO:0030279 - negative regulation of ossification
GO:0048546 - digestive tract morphogenesis
GO:0030036 - actin cytoskeleton organization
GO:0030097 - hemopoiesis
GO:2000271 - positive regulation of fibroblast apoptosis
GO:0048147 - negative regulation of fibroblast proliferation
GO:0008584 - male gonad development
GO:0005737 - cytoplasm
GO:0034446 - substrate adhesion-dependent cell spreading
GO:0050680 - negative regulation of epithelial cell proliferation
GO:0001756 - somitogenesis
GO:0090175 - regulation of establishment of planar polarity
GO:0042802 - identical protein binding
GO:0014034 - neural crest cell fate commitment
GO:2000117 - negative regulation of cysteine-type endopeptidase activity
GO:0002244 - hemopoietic progenitor cell differentiation
GO:0001944 - vasculature development
GO:0008585 - female gonad development
GO:0090246 - convergent extension involved in somitogenesis
GO:0060071 - Wnt receptor signaling pathway, planar cell polarity pathway
GO:0005109 - frizzled binding
GO:0009952 - anterior/posterior pattern specification
GO:0007420 - brain development
GO:0046851 - negative regulation of bone remodeling
GO:0043066 - negative regulation of apoptotic process
GO:0030336 - negative regulation of cell migration
GO:0071481 - cellular response to X-ray
GO:0009986 - cell surface
GO:0043508 - negative regulation of JUN kinase activity
GO:0042813 - Wnt-activated receptor activity
GO:0008201 - heparin binding
GO:0035019 - somatic stem cell maintenance
GO:0030154 - cell differentiation
GO:0060346 - bone trabecula formation
GO:0060218 - hemopoietic stem cell differentiation
GO:0014070 - response to organic cyclic compound
GO:0090090 - negative regulation of canonical Wnt receptor signaling pathway
GO:0030514 - negative regulation of BMP signaling pathway
GO:0017147 - Wnt-protein binding
GO:0046676 - negative regulation of insulin secretion
GO:0031012 - extracellular matrix
GO:0007275 - multicellular organismal development
GO:0045671 - negative regulation of osteoclast differentiation
GO:0042493 - response to drug
GO:0060070 - canonical Wnt receptor signaling pathway
GO:0071391 - cellular response to estrogen stimulus
GO:0008285 - negative regulation of cell proliferation
GO:0090244 - Wnt receptor signaling pathway involved in somitogenesis
GO:0010629 - negative regulation of gene expression
GO:0043065 - positive regulation of apoptotic process
GO:0045880 - positive regulation of smoothened signaling pathway