NIA Mouse Gene Index, mm9

2866. U043472
Annotation: leucine-rich repeat kinase 2     Gene?: Yes     Source: NM_025730    Symbol:  Lrrk2
Chromosome: chr15   Strand: +    Start: 91503605    End: 91646555
List: Positive strand of chr15 (N=3503)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR003579 - Ras small GTPase, Rab type
IPR006689 - ARF/SAR superfamily
IPR003593 - AAA+ ATPase, core
IPR003578 - Ras small GTPase, Rho type
IPR002041 - Ran GTPase
IPR000719 - Protein kinase, core
IPR001245 - Tyrosine protein kinase
IPR013753 - Ras
IPR002290 - Serine/threonine protein kinase
IPR013684 - Miro-like
IPR006688 - ADP-ribosylation factor
IPR003577 - Ras small GTPase, Ras type

GO-Ontologies
GO:0060161 - positive regulation of dopamine receptor signaling pathway
GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0005096 - GTPase activator activity
GO:0004708 - MAP kinase kinase activity
GO:0004672 - protein kinase activity
GO:0000165 - MAPKKK cascade
GO:0005737 - cytoplasm
GO:0021772 - olfactory bulb development
GO:0043547 - positive regulation of GTPase activity
GO:0008340 - determination of adult lifespan
GO:0005524 - ATP binding
GO:0035564 - regulation of kidney size
GO:0005624 - membrane fraction
GO:0000166 - nucleotide binding
GO:0043068 - positive regulation of programmed cell death
GO:0018105 - peptidyl-serine phosphorylation
GO:0016301 - kinase activity
GO:0048312 - intracellular distribution of mitochondria
GO:0040012 - regulation of locomotion
GO:0010942 - positive regulation of cell death
GO:0010508 - positive regulation of autophagy
GO:0015631 - tubulin binding
GO:0035640 - exploration behavior
GO:0045121 - membrane raft
GO:0042391 - regulation of membrane potential
GO:0016772 - transferase activity, transferring phosphorus-containing groups
GO:0016740 - transferase activity
GO:0046777 - protein autophosphorylation
GO:0061002 - negative regulation of dendritic spine morphogenesis
GO:0004674 - protein serine/threonine kinase activity
GO:0005488 - binding
GO:0000186 - activation of MAPKK activity
GO:0005622 - intracellular
GO:0006468 - protein phosphorylation
GO:0005802 - trans-Golgi network
GO:0007528 - neuromuscular junction development
GO:0007406 - negative regulation of neuroblast proliferation
GO:0030425 - dendrite
GO:2000173 - negative regulation of branching morphogenesis of a nerve
GO:0016310 - phosphorylation
GO:0032473 - external side of mitochondrial outer membrane
GO:0070997 - neuron death
GO:0005525 - GTP binding
GO:0042803 - protein homodimerization activity
GO:0005792 - microsome
GO:0034211 - GTP-dependent protein kinase activity
GO:0031398 - positive regulation of protein ubiquitination
GO:0022028 - tangential migration from the subventricular zone to the olfactory bulb
GO:0005886 - plasma membrane
GO:0030424 - axon
GO:0014043 - negative regulation of neuron maturation
GO:0007264 - small GTPase mediated signal transduction
GO:0001934 - positive regulation of protein phosphorylation
GO:0006979 - response to oxidative stress
GO:0019717 - synaptosome
GO:0008021 - synaptic vesicle