NIA Mouse Gene Index, mm9

1859. U089318
Annotation: sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)     Gene?: Yes     Source: NM_019812    Symbol:  Sirt1
Chromosome: chr10   Strand: -    Start: 62781752    End: 62801783
List: Negative strand of chr10 (N=4214)

Genome Browsers: NCBI - UCSC - Ensembl
View Regulatory Regions


Exon structure

Domains
IPR003000 - Silent information regulator protein Sir2

GO-Ontologies
GO:0051287 - NAD binding
GO:0016787 - hydrolase activity
GO:0003677 - DNA binding
GO:0016564 - transcription repressor activity
GO:0046872 - metal ion binding
GO:0006350 - transcription
GO:0030154 - cell differentiation
GO:0007283 - spermatogenesis
GO:0016481 - negative regulation of transcription
GO:0008270 - zinc ion binding
GO:0005677 - chromatin silencing complex
GO:0007275 - multicellular organismal development
GO:0006342 - chromatin silencing
GO:0017136 - NAD-dependent histone deacetylase activity
GO:0007519 - skeletal muscle development
GO:0001542 - ovulation from ovarian follicle
GO:0005634 - nucleus
GO:0016575 - histone deacetylation
GO:0006355 - regulation of transcription, DNA-dependent
GO:0006476 - protein amino acid deacetylation
GO:0006915 - apoptosis